ChemistryOpen‘s Issue 5 is now live!
ChemistryOpen’s latest issue is now available online and holds more exciting new articles, of which all are fully open access, meaning free to read, download and share.
For instance, D. Hinderberger and co-workers at the Max Planck Institute for Polymer Research (Mainz, Germany) observe Highly Defined, Colloid-Like Ionic Clusters in Solution. They show that their ions are not distributed randomly in solution but are well-ordered and electrostatically self-assemble into supramolecular structures (ionoids). A Platform for Specific Delivery of Lanthanide-Scandium Mixed-Metal Cluster Fullerenes into Target Cells is set up by L. Dunsch and colleagues at the Leibniz Institute for Solid State and Material Research (Dresden, Germany). They created a modular shuttle system consisting of a c-myc-antisense oligonucleotide and a cell-penetrating peptide to achieve an intracellular localization of gadolinium-containing nitride clusters, thereby facilitating specific delivery into cells.
Issue 5 also features two excellent back-to-back articles by Shibata and co-workers from the Nagoya Institute of Technology (Nagoya, Japan). While they analyze the C/O regioselectivity in Electrophilic Tri-, Di- and Monofluoromethylations of β-Ketoesters in correlation with the cationic versus radical nature of the intermediately formed species in one article, they report on an Efficient Difluoromethylation of sp3 Carbon Nucleophiles by Bromodifluoromethylation Reagents with Organic Bases in the other. Furthermore, D.-H. Zhang and M. Shi from the Shanghai Institute of Organic Chemistry (Shanghai, China) present a Highly Stereoselective Synthesis of Polycyclic Indoles through sequential catalysis of rearrangement and [4+2] cycloaddition under mild conditions and allowing various substitutions.