Top articles from Brain and Behavior Issue 2.4
Highlighted below are two articles from this issue selected by Editor-in-Chief Andrei Alexandrov:
Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica
Stephen L. Carlson, Andrew T. Kempsell and Lynne A. Fieber
Abstract: D-Aspartate (D-Asp) activates a Na+ and K+ current of unknown identity independent of L-glutamate (L-Glu) in neurons of Aplysia californica. Portions of D-Asp currents were blocked by L-Glu antagonists including kynurenate and APV, but L-Glu currents were unaffected by APV, and showed greater block by kynurenate, suggesting that D-Asp and L-Glu may act at different sites. The mixed pharmacological results as well as an asymmetrical desensitization by D-Asp of L-Glu currents suggest that D-Asp channels in Aplysia are not uniformly characteristic of any known agonist-associated channel type.
The relationship between nerve conduction velocity and fiber morphology during peripheral nerve regeneration
Masayoshi Ikeda and Yoshinori Oka
Abstract: The regression relation between fiber diameter and internodal length was not a sensitive index of recovery. MCV and mean fiber diameter were the most sensitive indices of functional recovery during sciatic nerve regeneration.