MicrobiologyOpen publishes its Second Issue
Issue 1.2 of MicrobiologyOpen is now live. Highlighted below are two papers which have been selected by our Editor-in-Chief, Pierre Cornelis:
Expression of a small (p)ppGpp synthetase, YwaC, in the (p)ppGpp0 mutant of Bacillus subtilis triggers YvyD-dependent dimerization of ribosome by Kazumi Tagami, Hideaki Nanamiya, Yuka Kazo, Marie Maehashi, Shota Suzuki, Eri Namba, Masahiro Hoshiya, Ryo Hanai, Yuzuru Tozawa, Takuya Morimoto, Naotake Ogasawara, Yasushi Kageyama, Katsutoshi Ara, Katsuya Ozaki, Masaki Yoshida, Haruko Kuroiwa, Tsuneyoshi Kuroiwa, Yoshiaki Ohashi and Fujio Kawamura
Summary: Dimerization of 70S ribosome was induced by the expression of ywaC gene in the delta-relA, delta-yjbM and delta-ywaC triple mutant of Bacillus subtilis.
Human mitochondrial ferritin improves respiratory function in yeast mutants deficient in iron–sulfur cluster biogenesis, but is not a functional homologue of yeast frataxin by Robert Sutak, Alexandra Seguin, Ricardo Garcia-Serres, Jean-Louis Oddou, Andrew Dancis, Jan Tachezy, Jean-Marc Latour, Jean-Michel Camadro and Emmanuel Lesuisse
Abstract: Expression of human mitochondrial ferritin in frataxin-deficient yeast cells (yfh1) improved the respiratory function of the cells. But this effect was also observed in another mutant impaired in iron-sulfur cluster assembly (ggc1). Expression of human mitochondrial ferritin in yeast FeS mutants generated a small pool of high spin ferrous iron in the mitochondria, resulting in an improvement of heme synthesis in these mutants.
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